MICROFLUIDIC HIGH-MIGRATORY CELL COLLECTOR SUPPRESSING ARTIFACTS CAUSED BY MICROSTRUCTURES

Microfluidic High-Migratory Cell Collector Suppressing Artifacts Caused by Microstructures

Microfluidic High-Migratory Cell Collector Suppressing Artifacts Caused by Microstructures

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The small number of high-migratory cancer cells in a cell population make studies on high-migratory cancer cells difficult.For the development of migration assays grundfos scala1 3-45-1 115v 60 hz 99631742 for such cancer cells, several microfluidic devices have been developed.However, they measure migration that is influenced by microstructures and they collect not only high-migratory cells, but also surrounding cells.In order to find high-migratory cells in cell populations while suppressing artifacts and to collect these cells while minimizing damages, we developed a microfluidic high-migratory cell collector with cadbury eclairs chocolate price the ability to sort cancer cells according to cellular migration and mechanical detachment.High-migratory cancer cells travel further from the starting line when all of the cells are seeded on the same starting line.

The high-migratory cells are detached using a stretch of cell adhesive surface using a water-driven balloon actuator.Using this cell collector, we selected high-migratory HeLa cells that migrated about 100 μm in 12 h and collected the cells.

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